Rodriguez wins stage two, takes GC lead
The Spaniard, who narrowly lost out to compatriot Samuel Sanchez on day one, made a break on the final seven kilometres on the hilltop finish of El Castillo to not only secure the win but also takeover at the top of the general classification.
Rodriguez was followed over the line by Katusha team-mate Daniel Moreno, three seconds adrift, while Sanchez finished third, seven seconds behind Rodriguez.
Rodriguez now leads Sanchez by seven seconds in the GC while David Lopez holds third, 17 seconds back.
The early stages of the route were dominated by a breakaway from Etienne Tortelier (Saur-Sojasun) and Kenny de Ketele (Topsport Vlaanderen-Mercator), the duo being joined by Jordi Simon (Caja Rural) and Carlos Verona (Burgos 2016-Castilla y Leon) with 30km remaining.
The peloton caught the breakaway quartet with 13.5km left of the circuit, although Simon launched a last gasp attack only to be reeled in with 12km left.
Heading into the final 7km, Katusha made their decisive break before Rodriguez pulled away on the final ascent.