Berdych romps into Beijing quarters
The third-seeded Czech is one of only two seeds left in the competition and will next face Spain's Fernando Verdasco.
Berdych won the match in little over an hour despite a poor first service percentage of just 45 per cent.
The only other seed left is top-seeded Frenchman Jo-Wilfried Tsonga who faces local player Ze Zhang in the second round on Thursday.
Verdasco came from a set behind against Italy's Flavio Cipolla to win his second-round clash 2-6 6-1 6-2.
"It was a very difficult match," Verdasco told the ATP website.
"He was a player I had never played before. It is always tricky at the start, when you are trying to figure out his strengths and weaknesses."
Croatia's Ivan Ljubicic fired 13 aces on his way to a 6-0 2-6 6-3 win over Germany's Florian Mayer and will be Youzhny's quarter-final opponent.