The Uruguay international has been strongly linked with a move away from Bologna and is a target of several top European clubs.
"I can confirmed that Juventus and Manchester City have contacted me to show an interest," Ramirez's representative Betancourt said to www.calciomercato.com.
"But there is especially an interesting offer from Wolfsburg and also another one from an important Spanish club.
"I think considering all the offers, the possibility that he could leave (this summer) could happen.
"I would like to point out that there are several agents working on the player but from June 1, I will have his exclusive rights."