The New Zealand central defender may be rested after suffering stiffness in his troubled hamstring.
Nelsen came off at the start of the second half against City and was replaced by Zurab Khizanishvili.
Hughes said: "Ryan's mobility was being affected but we are not too concerned.
"As with all long-term injuries sometimes you get little niggles after an operation."
I'm sure this match is on everyone's radar for the weekend. Neal is sure to pimp MGP and BFDB. But before you go and put big money downRead More »from Kiwi Questionable