Gloucester sealed their passage into the Challenge Cup last-16 after thrashing Perpignan, while Worcester gave themselves hope by beating Zebre.
Elsewhere, there were huge wins for Manchester United and Newcastle.
Reigning champions City were unable to stretch their winning run to 13 top-flight games.
Harry Randall signed off for England duty with another inspiring performance as Bristol served up a eight-try thrashing of Scarlets. The young scrum-half will hope to get a taste of six Nations action in the coming weeks but will be delighted at having helped Bears finish their pool stage with another victory and they can now look forward to the knockout stage of the Champions Cup.