The Boston Celtics led by eight points at half-time before the Miami Heat's remarkable 39-14 turnaround.
Yuli Gurriel, Michael Brantley, Jeremy Pena, Kyle Tucker and Yordan Alvarez all homered for the Houston Astros in one inning.
The Blades captain was sidelined for the second leg because of injury prior to the incident.
Boca Juniors could only manage a point against 10-man Corinthians, while Flamengo and Estudiantes won in the Copa Libertadores on Tuesday.