Wales head coach Warren Gatland has made wholesale changes to his starting line-up for their Six Nations clash with Scotland at Murrayfield.
The trio boast 342 caps and 18 Lions Test appearances between them.
The number of black and ethnic minority players selected for England women youth teams has increased by 10% since 2017
Italy have never beaten England and as such the hosts are clear favourites. However, the Azzurri are an improving outfit and it would be no shock to see them ask more questions of this England side at Twickenham than they have done before.