Oscar failed from the penalty spot twice as Shanghai SIPG's 100 per cent record in the AFC Champions League came to an abrupt halt against Urawa Red Diamonds.
The former Chelsea forward had scored in his previous four appearances in the continental competition, but could not add to his tally in Tuesday's 1-0 loss.
Shanghai fell behind a minute before half-time in their Group F clash as Rafael Silva pounced on a loose ball to fire across Yan Junling.
The Chinese Super League side were given two chances to salvage something from the clash, but Oscar – the most expensive CSL signing – could not take advantage.
His first opportunity came after 65 minutes when he was hauled down in the area, but Shusaku Nishikawa made a superb save to palm it onto the crossbar.
Nishikawa did not need to do anything with the second spot kick 11 minutes later, as Oscar blazed it over the bar after Tomoaki Makino had handled.
The result moved Urawa above Shanghai and into top spot in the group, but Oscar's side are still well placed to qualify, with a six-point cushion over third-placed Seoul – who beat Western Sydney Wanderers 3-2 thanks in part to a Dejan Damjanovic double.
KNOCKOUT STAGE BECKONS FOR RAMPANT JIANGSU
Jiangsu Suning are the first side into the knockout stages after another impressive Group H display, their overseas imports coming to the fore in a 3-0 win over Gamba Osaka.
Alex Teixeira and Ramires gave the CSL side immediate control with goals inside the opening 10 minutes - the latter notching his third goal of the competition.
Teixeira then turned provided as Hong Jeong-ho headed Jiangu's third before the break, Choi Yong-soo's side able to cruise to a fourth successive victory in the second half.
Adelaide United occupy second place behind Jiangsu thanks to second-half goals from Dylan McGowan and Riley McGree, the A-League side securing a 3-1 win over Jeju United.
A late equaliser from Kaveh Rezaei snatched a point for Group A leaders Esteghlal in Tashkent, the striker placing an 87th-minute controlled finish into the bottom corner to cancel out Marat Bikmaev's opener for Lokomotiv.