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England centre-back White missed the wins over West Ham and Leeds with a hamstring issue, while Saka was substituted against the latter on Sunday after suffering a knock.
Both were in a race against time to be fit for a crunch meeting with rivals Spurs in the race for Champions League qualification.
“Thomas [Partey] is still out, Kieran [Tierney] is still out and with Ben he is still a doubt, we have to assess him and see how he is feeling, which is much better,” Arsenal boss Mikel Arteta told reporters on Wednesday. “With Bukayo, it’s the same.
“It’s very difficult to rate with injuries, it’s just how they feel today. That’s the last day that we can assess them and try to get the feeling, basically.”
The Gunners did the same against Chelsea last month, when they matched their opponents’ system perfectly en route to a memorable 4-2 win at Stamford Bridge.
Predicted Arsenal XI (3-4-2-1): Ramsdale; Cedric, Holding, Gabriel; Tomiyasu, Elneny, Xhaka, Saka; Odegaard, Smith Rowe; Nketiah
When: Tonight, 7.45pm BST, Sky Sports
Venue: Tottenham Hotspur Stadium
Referee: Paul Tierney
Arsenal squad from: Leno, Ramsdale, Okonkwo; Cedric, Gabriel, Holding, Tavares, Tomiyasu, White; Elneny, Lokonga, Odegaard, Patino, Saka, Smith Rowe, Xhaka; Lacazette, Martinelli, Nketiah and Pepe.
Injured: Partey (thigh), Tierney (knee)
Doubts: Saka (knock), White (hamstring)