The 27-year-old could only reach the semi-finals at London 2012, but in Doha she took the scalp of Olympic silver medallist Lashinda Demus as she cross the line third.
And there was plenty more for the Scot to celebrate as her time of 55.43 seconds was her fastest ever outdoor season opener.
In her first outdoor track appearance since the Zurich Diamond League in September 2011, Jenny Meadows finished the 800m in seventh with a time of 2:00.91 minutes, while compatriot Shelayna Oskan-Clarke clocked a massive lifetime best of 2:01.94 taking over a second-and-a-half off her previous best to finish ninth.
In the men's 800m Andrew Osagie went head-to-head with world champion Mohammad Aman and Olympic silver medallist Nijel Amos, finishing eighth place in 1:46.08.
Brett Morse threw a best of 58.35m to finish ninth in the discus, an event won by world silver medallist Piotr Malachowski with an effort of 66.72m.
However there was disappointment for Chris Tomlinson with the 32-year-old failing to register a mark in the long jump.
- Sports & Recreation
- Lashinda Demus