The striker left Bayern in the summer in what appeared at various points to be an acrimonious departure and he already has nine goals, including a Champions League hat-trick, to his name for Barcelona.
He was part of a Bayern side that in recent years have proved far too good against the La Liga club when they have met, but Xavi and his team are in far better shape than they have been for many seasons.
It promises to be an entertaining night in Munich, with both sides looking to build on a winning start to their Group C campaign.
Date, kick-off time and venue
Bayern Munich vs Barcelona is scheduled for an 8pm BST kick-off on Tuesday, September 13, 2022.
The Allianz Arena in Munich will host the match.
Where to watch Bayern Munich vs Barcelona
TV channel: The match will be televised on BT Sport 4, with coverage starting following Tottenham’s game earlier in the evening.
Live stream: BT Sport subscribers will be able to watch the match online via the BT Sport website or app.
Live blog: You can follow all the action via Standard Sport’s live blog.
Bayern Munich vs Barcelona team news
Bayern XI: Neuer, Pavard, Upamecano, Hernandez, Davies, Kimmich, Sabitzer, Sane, Muller, Musiala, Mane.
Subs: De Ligt, Gnabry, Goretzka, Choupo-Moting, Ulreich, Gravenberch, Tel, Mazraoui, Stanisic.
Barcelona XI: Ter Stegen, Kounde, Araujo, Christensen, Alonso, Gavi, Busquets, Gonzalez, Raphinha, Lewandowski, Dembele.
Subs: Bellerin, Pique, Fati, Torres, Depay, Jordi Alba, Kessie, de Jong, Garcia, Pena, Balde, Tenas.
Bayern Munich vs Barcelona prediction
Bayern have not been entirely convincing domestically in the early weeks of the season, drawing their last three games.
Barcelona, meanwhile, have scored 15 goals and conceded just one in their first five league matches with Lewandowski quickly setting into life in Spain.
Goals are certainly on the cards at the Allianz Arena - Bayern have the quality to just about edge a thrilling encounter.
Bayern to win, 3-2.
Head to head (h2h) history and results
The sides met last season in the Champions League, when Bayern won both group-stage matches 3-0. In 2020, the German giants beat Barcelona 8-2 in the quarter-finals.
Bayern Munich wins: 8
Barcelona wins: 2