Londoner Chisora is relishing the fight and is promising to pull off a huge upset as he targets a second world title shot.
Chisora beat Argentine Hector Alfredo Avila last month at Wembley, stopping him in the ninth round - his first fight since his loss to David Haye in July last year - and sees the knockout specialist Wilder as his route back to the top.
Alabama's Wilder, known as 'The Bronze Bomber', has knocked out all 28 of his opponents with a staggering 26 of them coming inside three rounds. The Beijing 2008 Olympics bronze medallist ended the career of Britain’s Audley Harrison last month, blitzing the Sydney 2000 gold medallist inside 70 seconds in his UK debut.
"I'm excited and I needed something like this to happen," said Chisora.
"I first saw Wilder two years ago and I said to my trainer it would be a great fight for me. He has been protected but not anymore.
"He brings nothing I've not seen before and I can't wait for the fight."
Promoter Frank Warren added: "Dereck needs big fights like this to get motivated. He's now had 20 fights, 8 less than Wilder, but he hasn't fought anyone like Dereck or the quality Dereck has. Golden Boy are obviously confident in Wilder. We'll see."
Chief support on the card sees an all-British showdown between two unbeaten young champions in Frankie Gavin and Denton Vassell.
Birmingham's Gavin, the British welterweight champion, makes the second defence of his title against Vassell, who is also putting his Commonwealth title on the line. Gavin won the title by outpointing Junior Witter last November and defended against Jason Welborn in January with a seventh round stoppage.
Unbeaten in 15 fights with 11 KO’s, Gavin - still Britain’s only ever world amateur champion - faces the toughest test of his career against his undefeated Manchester rival. Vassell has already claimed the scalp of a hot unbeaten prospect in Ronnie Heffron last November, stopping him in six rounds and will have no fear facing Gavin.
Ellesmere Port’s Paul Butler returns to London and aims to add a third title in back-to-back fights when he challenges for the vacant WBO intercontinental super-flyweight title. Butler, who holds the British strap, won the Commonwealth belt last month at Wembley Arena with a devastating performance against Yaqub Kareem, stopping the champion inside five rounds.
Liverpool warriors Paul Smith and Tony Dodson meet again in a rematch with the British super-middleweight title up for grabs.
The pair clashed over three years ago in a bloody and brutal battle that saw Smith, then British champion, suffer two cuts above his eye in the opening round from head clashes and take some heavy shots from Dodson, but he battled back with a powerful performance to win on the judges’ scorecards.
Unbeaten London super-middleweight Frank Buglioni continues his meteoric rise and features in an eight-round contest on the undercard as he targets a first title shot. The hard-hitting 24-year-old made it six KOs out of eight fights with his third round KO of Darren McKenna last time out at Wembley Arena.
The undercard features unbeaten light-heavyweight and 2010 Commonwealth Games Champion Calum Johnson from Boston; Southern Area Welterweight Champion Bradley Skeete; Former Southern Area Light-Middleweight Champion Steve O’Meara; Wembley Light-Welterweight Gary Corcoran; Harrow Weald Super-Featherweight Mitchell Smith; Canning Town lightweight Billy Morgan; Chingford’s unbeaten Tom Baker and Bowers Gifford John Dignum clash over four rounds at middleweight; plus Islington super-featherweight Joey Taylor.
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