Last season, the Bees famously beat the Gunners 2-0 to mark their first game in the Premier League with a huge scalp, which proved to be a demoralising blow for Mikel Arteta’s side.
A poor run followed that night and Arsenal narrowly missed out on a top-four spot - but this time around, they head across the capital already in fine fettle.
Brentford are also in form and both teams have only tasted a single defeat so far this campaign, making for an intriguing lunchtime match-up.
Where to watch Brentford vs Arsenal
TV channel: The match will be televised on Sky Sports Main Event and Premier League, which coverage starting at 11.30am BST ahead of a noon kick-off.
Live stream: Sky Sports subscribers will be able to watch the match online via the Sky Go app.
Live blog: You can follow all the action via Standard Sport’s live blog, with Simon Collings on location to provide expert analysis.