Beaten by Brighton during his first game in charge of the club, Graham Potter’s well-coached side exposed some of the flaws in United’s team.
At an early stage of their rebuild under new management, there are more than a few teething problems for the Dutchman.
Thomas Frank, meanwhile, has given some of the Premier League’s biggest teams a run for their money, particularly at the Gtech Community Stadium.
A difficult place to go against a side well-versed in exactly what their coach wants, the home team will not be fearful of this incarnation of Manchester United.
Here’s how to keep across the game…
Where to watch Brentford vs Manchester United
TV channel: Today’s match will be televised live on Sky Sports Premier League and Main Event, with coverage starting at 5pm BST ahead of a 5:30pm kick-off.
Live stream: Sky Sports subscribers will be able to watch the game online via the Sky Go app.
Live blog: You can also follow all the action via Standard Sport’s live blog, with expert analysis from Malik Ouzia at the stadium.