The Foxes have been hard-hit by injuries to the likes of James Maddison and Harvey Barnes of late, with a draw against Burnley in midweek leaving them third in the table but with just two wins from their last five.
That comes in addition to being knocked out of the Europa League by Slavia Prague, which will no doubt leave Brendan Rodgers with mixed feelings: little chance of silverware for the season, but more time to rest up between league games and try to secure a top-four finish.
Brighton, meanwhile, remain in 16th position after two wins and two defeats in their last four; they are above Newcastle only on goal difference and just three points above the relegation zone as their goalscoring problems continue to affect their survival chances.
Here’s everything you need to know ahead of the match at the Amex Stadium.
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When is the game?
The match kicks off at 8pm on Saturday, 6 March.
Where can I watch it?
The game will be shown live on Sky Sports Main Event, Sky Sports Premier League and Ultra HD channels. Subscribers can stream the fixture via the Sky Go app.
If you’re not a Sky customer you can grab a NOWTV Day Pass here to watch without a subscription.
What is the team news?
Both teams have injury worries, with Brighton recently finding out that wing-back Tariq Lamptey has had a setback with his hamstring injury. Solly March and Adam Webster are also out and Aaron Connolly is expected to miss this game.
Leicester will be without Harvey Barnes for around six to eight weeks and James Justin for the foreseeable future, while Dennis Praet and Wes Morgan are also absent. James Maddison, Jonny Evans and Ayoze Perez must be assessed.
BRI - Sanchez; Veltman, White, Dunk, Burn; Alzate, Bissouma, Gross; Mac Allister; Welbeck, Trossard
LEI - Schmeichel; Amartey, Fofana, Soyuncu; Pereira, Tielemans, Ndidi, Mendy, Castagne; Vardy, Iheanacho
Brighton - 18/11
Draw - 45/19
Leicester - 39/19
The Seagulls are running short of games to find the right combination in the final third but they might just find a route through a patchwork Leicester defence. Brighton 2-1 Leicester.