The foursome of Jackson, Dan Money, Allyn Condon and Henry Nwume began their campaign well enough and placed 11th after heat one.
But they could not follow suit on their second run on the lightning fast Whistler track as they crashed at the treacherous corner 13, dubbed 50-50 by competitors in reference to the chances of remaining upright.
Medical staff rushed to greet the British quartet but there were no serious injuries, only bruised egos with Money hurling his helmet onto the ice in frustration.
Money and Jackson had also crashed in the opening run of their two-man bobsleigh campaign, again at corner 13.
Great Britain are not the only four-man crew to struggle in Vancouver however, as 11 out of the 29 teams have suffered a crash at some stage in Whistler.
But it does compound a miserable bobsleigh showing from Great Britain in Whistler with Jackson crashing in both competitions, while reigning world champions Nicola Minichiello and Gillian Cooke suffered a spill on their third run.