After dropping the opening frame, Selby put together runs of 61 and 120 to take the lead before doubling his advantage in a scrappy fourth frame, notching another half-century in the process.
And after the world number one missed a chance to mount a comeback in frame five and was pegged back to 3-2, another century (101) and an 88 moved the 'Jester from Leicester' into the next round where either Martin Gould or Jamie Cope await.
In wild card qualifiers, Jamie Burnett and Rod Lawler overcame local opposition to reach the first round proper. Lawler defeated Li Hang 5-2 while Burnett overcame Jin Hong 5-3
Lawler will now play World Championship semi-finalist Stephen Maguire in the first round proper, while 2010 World kingpin Neil Robertson is next for Burnett.
Dave Harold, meanwhile, will play no further part after a 5-1 loss to Rouzi Maimaiti, who now faces infamous Mark Allen in the opening round.
Robert Milkins will take on Andrew Higginson after a 5-2 victory over Chen Feilong at the wild card stage.
Fergal O'Brien also progressed by a 5-2 scoreline against Lu Haotian, with 2012 Crucible finalist Ali Carter next up for the Irishman.
And Zhu Yinghui impressed in defeating Michael Holt 5-1 to secure a contest with Ricky Walden.
The winner of that will take on Joe Perry, who received a walkover into the second round after scheduled opponent Matthew Stevens pulled out with a back problem.