Sam Kerr broke the deadlock in the early stages, the Australian international producing a thumping left-footed volley past Aston Villa goalkeeper Lisa Weiss.
Kerr turned provider and executed a precise cross to find striker Bethany England, who headed the ball into the top corner as Chelsea doubled their lead before half-time.
In the second half, Emma Hayes' side continued from where they left off.
Pernille Harder glided a low drive into the bottom right-corner to give the Blues their third goal of the game.
And Chelsea claimed a four-goal cushion before the hour mark when Blues skipper Magdalena Eriksson slotted the ball into the far post to secure the three points.
Additional reporting by PA.