Mauricio Pochettino has overseen just one win in six Premier League games and his Blues side scrapped past AFC Wimbledon in the previous round.
Brighton, meanwhile, are flying high and will be confident of recording a third consecutive win over a Chelsea side who have hired (and then fired) their manager and signed arguably their best player in the last year.
Date, kick-off time and venue
Chelsea vs Brighton is scheduled for a 7.45pm BST kick-off tonight on Wednesday, September 27, 2023.
The match will take place at Stamford Bridge.
Where to watch Chelsea vs Brighton
TV channel and live stream: In the UK, the game has not been picked for television coverage.
Highlights: Sky Sports’ official Twiter and YouTube channels will show highlights after the game, while ITV 1 will offer a highlights show at 12.05am BST on Thursday 28 September.
Live blog: However, you can follow all the action on matchday via Standard Sport’s live blog, with expert analysis from Nizaar Kinsella at the ground.
Chelsea vs Brighton team news
It will be interesting to see how both managers approach the game. In a stark sign of the times, it could be Brighton not Chelsea who opt to make more changes as they compete on more fronts and further up the table while the Blues could do with a win of any sort.
Goalkeeper Djordje Petrovic should make his debut, and fellow summer signing Cole Palmer will join him in an otherwise strong XI. You would imagine Ben Chilwell starts and takes the captain’s armband. Axel Disasi looks a safe bet to start at right-back, while Nicolas Jackson is available despite Premier League suspension.
Brighton should also change their keepers with Jason Steele coming in, and could give another start to loanee Ansu Fati. Adam Lallana should also feature, along with former Chelsea midfielder Billy Gilmour.
Chelsea vs Brighton prediction
It feels like whatever team Brighton put out, their confidence - and Chelsea’s lack of it - will see them win whoever is in front of them. This is a team playing with no fear, against a team heading in the opposite direction and with sections of the fanbase already turning on the manager.
Mauricio Pochettino still has plenty of injuries and suspensions to juggle, meaning his options are limited to change things too much, so I cannot see too much improvement unless Roberto De Zerbi opts for a far weaker XI.
Brighton to win in extra time.
Head to head (h2h) history and results
Chelsea have lost the last two games between these sides, and last beat the Seagulls three years ago, a run dating back six games.
Chelsea wins: 12
Brighton wins: 3
Chelsea vs Brighton match odds
Ansu Fati to score: 5/2
Odds via Betfair (subject to change).