The Uruguayan defender hasn't made much of an impact following his move to Anfield in the summer but scored an absolute screamer in the 3-2 loss to QPR.
His stunning scissor-kick at Loftus Road claimed 46 per cent of the vote among Eurosport-Yahoo! readers.
Javier Hernandez claimed second spot with his fine finish following a nice move from Manchester United in the 5-0 destruction of Wolves, while Sami Nasri's winner against Chelsea came second.
1. Sebastian Coates (Liverpool) v QPR - 46%
2. Javier Hernandez (Manchester United) second goal v Wolves - 23%
3. Samir Nasri (Manchester City) v Chelsea - 19%
4. Papiss Cisse (Newcastle) v Norwich - 8%
5. Gylfi Sigurdsson (Swansea) second goal v Fulham - 4%