MADRID (Reuters) - Alcoyano's fairytale Copa del Rey run came to an end when they were beaten 2-1 by Athletic Bilbao in the last 16 on Thursday.
Third tier Alcoyano, who knocked out Real Madrid in the last round, looked on course for another upset when they took the lead through Pablo Carbonell's deflected free kick six minutes before the break.
Asier Villalibre's towering header levelled the scores on 53 minutes, however, before Inaki Williams nodded in the winner 12 minutes from time to book Bilbao's place in the last eight.
Earlier on Thursday, Navalcarnero, the other third tier side left in the competition, were crushed 6-0 by La Liga team Granada.
They joined Barcelona, Villarreal, Sevilla, Levante, Real Betis and Almeria in the hat for the quarter-final draw on Friday.
(Reporting by Joseph Walker, editing by Ed Osmond)