It was the sixth consecutive win for the Mavericks, which has coincided with a scintillating stretch of play from their Slovenian superstar.
Doncic scored 51 points against the Spurs on 18-of-29 shooting, adding nine assists, six rebounds and four steals. It came just four days after Doncic became the first player in NBA history to post a 60-point, 20-rebound, 10-assist game in a dramatic comeback against the New York Knicks.
The 23-year-old, who has a Rookie of the Year and three All-NBA First Team selections from his first four seasons, is mounting a charge for his first MVP, and has put together arguably the best five-game stretch of his career.
In his past five games, Doncic is averaging 45.6 points, 11.2 rebounds and 10.2 assists, and in the process he has overtaken Joel Embiid in the race for the scoring title, now at 34.2 points per game for the season.
Christian Wood was strong in a supporting role against the Spurs, scoring 25 points on 10-of-15 shooting. In his eight appearances since finally being injected into the starting line-up, Wood is averaging 19.0 points, 8.6 rebounds and 2.5 blocks while shooting 50.5 per cent from the field and 38.2 per cent from deep.
The Mavericks are now 21-16 and have jumped up to fourth place in the Western Conference.
Nets make it 11 in a row
The Brooklyn Nets remain the hottest team in the league after rattling off their 11th consecutive win, defeating the Charlotte Hornets 123-106.
Kyrie Irving led the way offensively with 28 points on 11-of-19 shooting, while Kevin Durant was similarly efficient for his 23 points (nine-of-15). Defensively, Nic Claxton was the anchor, blocking six shots while also hitting six of his seven field goal attempts.
After starting the season 1-5, the Nets are now 24-12, and trail only the Boston Celtics (26-10) in the Eastern Conference.
Morant takes bragging rights in 2019 Draft showdown
The New Orleans Pelicans selected Zion Williamson over Ja Morant in the 2019 NBA Draft, and they received a glimpse at what could have been as Morant guided the Memphis Grizzlies to a 116-101 triumph.
Morant scored a game-high 32 points on 13-of-22 shooting, adding eight assists and two steals, while Wiliamson could only muster 20 points on six-of-16 shooting and a career-high nine turnovers.
Having only played in 18 of the Grizzlies' 34 games, Jaren Jackson Jr does not qualify for the official league leaderboards, but his six blocks against the Pelicans raised his average to 3.0, comfortably clear of league-leader Brook Lopez (2.6).