Double division upsets as miserable Rodgers run continues and Bills also beaten

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Aaron Rodgers lost a fifth straight game for just the second time in his NFL career as the Green Bay Packers were upset again by NFC North rivals the Detroit Lions.

The Packers are enduring a torrid season and fell to 3-6 with this latest 15-9 defeat on Sunday.

Green Bay had not previously lost five in a row since 2008 – Rodgers' first year as a starter – but there is no sign of their misery ending any time soon.

Rodgers, previously so dominant in division matchups, threw three interceptions in a game for only the fifth time in his career and for the first time against NFC North opponents.

Two of those came with the game still scoreless, giving the lowly Lions a foothold they fought hard to protect.

Detroit had traded T.J. Hockenson within the division to the Minnesota Vikings at the deadline, but that void was filled by a pair of career-first touchdown catches from tight ends.

Shane Zylstra – elevated from the practice squad on Saturday alongside wide receiver brother Brandon – got the Lions on the board with his first catch of the year, while rookie James Mitchell's score at the start of the fourth quarter ultimately proved decisive.

Bills loss leaves AFC East in the balance

The fourth of Rodgers' five successive defeats had come against the Buffalo Bills last week, but Josh Allen was also on the end of a shock loss on Sunday as the New York Jets blew the AFC wide open. Despite two rushing TDs, Allen was every bit as hapless as Rodgers through the air as he threw two interceptions in the Jets' tense 20-17 win.

With the Bills 6-2 and the Jets 6-3, the AFC East is among the year's closest fought divisions, with the Miami Dolphins just about improving to 6-3 by fending off the Chicago Bears 35-32. Justin Fields kept the Bears in touch, throwing three TD passes and rushing for 178 yards – a Super Bowl era record among quarterbacks. His stunning 61-yard TD run was the longest of his career.

Mixon makes hay with Bengals' first five-TD game

There was no late drama in the game between the Cincinnati Bengals and the Carolina Panthers, which was dominated by running back Joe Mixon. He rushed for four TDs and had five total scores – also catching a Joe Burrow pass. It was just the ninth five-plus-TD game of the Super Bowl era – and the first by a Bengal – and set up a 42-21 victory.