Durant top scored with 27 points along with six rebounds, three assists, two steals and two blocks, while Curry drained four three-pointers in his 22 points off the bench. Nic Claxton also had 13 points with 14 rebounds.
Curry scored 14 points with two assists in the fourth quarter as the Nets extended their four-point lead with a 35-24 final period.
The Nets, who confirmed the permanent appointment of Jacque Vaughn as head coach on Wednesday, were excellent defensively again, keeping their opposition below 100 points for the fifth straight game.
Nets guard Edmond Sumner (11 points, four assists and three steals) reached double-figure scoring for the third time in five games since stepping into the starting lineup in place of Kyrie Irving for a team-imposed suspension.
Irving's five-game minimum suspension has now ended but Vaughn confirmed he would not play in Sunday's game against the Los Angeles Lakers. The victory starts the Nets' four-game road trip in style, improving Brooklyn to 6-7 on the season, while the Clippers are 7-6.
Doncic responds after form dip
Doncic had started the season with an historic run of nine 30-point games, but that was halted in the past two games, both where he scored less than 30.
The Slovenian guard turned that around on 13-of-22 field shooting, also making 15-of-18 from the stripe, along with 13 rebounds, 10 assists and two steals.
Tatum and Embiid both score 40-plus
Tatum finished with 43 points, including seven three-pointers, along with 10 rebounds and three assists. The Celtics small forward scored 28 of his points in a dominant first half.