Jack Rosser looks at three with a chance to shine...
With concerns over the fitness of Harry Maguire, Southgate will be keen to cast his eye over other options. A return to a back-three is a possibility — a move which would suit Coady well.
The Wolves defender has performed well in an England shirt and is at home bellowing orders in the middle of a three-man defence.
After all the noise around whether the Liverpool full-back would make the cut, now is the time to make an impact.
Alexander-Arnold has recovered his form since being left out of Southgate's last squad and could also be offered the chance to show what he can do in midfield in one of the warm-up matches.
Southgate claimed the La Liga winner was England's forgotten man when he announced his squad last night.
Trippier faces stiff competition at right-back but he is a firm favourite of Southgate's and the England boss likes his versatility. He could start at left-back tonight, when he can make his mark with a strong showing against Austria.