The 27-year-old, who has been on the podium three times this season, needed the 100 points on offer for the win to secure the overall Super-G title and she duly obliged taking her tally to 435 points.
Ilka Stuhec finished second on the day, 0.35 secs shy of Weirather’s time of 1:11.66, with Federica Brignone completing the podium.
Three-time world junior champion Stuhec, who sealed the World Cup Downhill title on Wednesday, had to settle for second spot in the overall Super-G standings, just five points behind Weirather.
Lindsey Vonn was 0.18 secs shy of Weirather at the second split as she chased a 78th World Cup win but straddled a gate before crashing.
RESULTS FROM THE WORLD CUP ASPEN, CO WOMEN'S SUPER G
1. Tina Weirather (Liechtenstein) 1:11.66
2. Ilka Stuhec (Slovenia) 1:12.01
3. Federica Brignone (Italy) 1:12.02
4. Nicole Schmidhofer (Austria) 1:12.40
5. Elisabeth Goergl (Austria) 1:13.00
6. Ricarda Haaser (Austria) 1:13.04
7. Christine Scheyer (Austria) 1:13.12
8. Viktoria Rebensburg (Germany) 1:13.31
9. Tessa Worley (France) 1:13.36
10. Elena Curtoni (Italy) 1:13.49
OVERALL SUPER-G STANDINGS
1. Tina Weirather (Liechtenstein) 435
2. Ilka Stuhec (Slovenia) 430
3. Lara Gut (Switzerland) 300
4. Elena Curtoni (Italy) 271
5. Stephanie Venier (Austria) 255
6. Sofia Goggia (Italy) 240
6=. Nicole Schmidhofer (Austria) 240
8. Federica Brignone (Italy) 222
9. Tessa Worley (France) 167
10. Kajsa Kling (Sweden) 156
Read the original article on Eurosport: Weirather claims Super-G title by five points with Aspen win