Neymar missed the match due to injury whilst Iniesta came off the bench but he was unable to change the game for his team.
They both start as Samuel Umiti returns to the back three alongside Gerard Pique and Javier Mascherano.
Iniesta plays next to Ivan Rakitic, Sergio Busquets and Rafinha with the MSN leading the line.
As for Valencia former Barca full-back Martin Montoya starts as does Munir, who is on loan from the Catalan side
Read the full article on eurosport.co.uk: Team news: Iniesta and Neymar return for Barcelona