The 26-year-old played the full 90 minutes of the Hammers' 3-2 defeat by Leicester, but manager Slaven Bilic revealed afterwards he had suffered a hamstring injury.
Bilic said: "He's probably going to be withdrawn from the England squad with a hamstring problem.
"He felt something. He played the whole game but the medical team have told me now. He didn't limp off, though, so we will see tomorrow."
Read the full article on eurosport.co.uk: Michail Antonio a doubt for England with hamstring injury