Murphy’s run of 89, 101, 101 and 104 in just five frames saw him book a clash with Gary Wilson, a 5-3 victor over Graeme Dott.
Stuart Bingham struck a match-high break of 96 as he beat Scott Donaldson 5-3.
Bingham reeled off the opening three frames to put himself in a commanding position before addressing a mini wobble with another half century in the final frame.
Jimmy White also progressed with a 5-1 win over wild card Li Yuan.
Meanwhile, Mark Selby recovered from a slow start to power into the first round - with his qualifying match held over to the venue stage.
Read the full article on eurosport.co.uk: Murphy, Bingham reach China Open second round