The pair shared the session with two frames apiece with Selby winning the first and last of the session.
After a really tense opening to the session, that saw over 11 minutes pass without a pot, Selby eventually sank a red to the middle and he potted very well to get a frame back.
However Higgins then cleared up very well on two occasions as he won the battle of the safety's.
But Selby came back in the last frame, taking advantage as Higgins failed to sink a crucial pink.
Having fought back on two occasions in the first mini-session to be level at 2-2 Higgins then took control in the second mini-session.
The second mini-session was blighted by both players failing to finish off frames and letting their opponents back in.
In the fifth Higgins let Selby in only to then find himself back on the table as his opponent was unable to dislodge the reds that had nestled on the side cushion, and Higgins made no mistake this time as he took a lead for the first time.
The sixth took a while to get going but when Higgins did find himself amongst the balls he made it count, making a break of 95.
Read the full article on eurosport.co.uk: Higgins cements lead at mid-session interval