QPR will now be without the veteran midfielder for the visit of Swansea City on Wednesday evening after Derry's one-match ban was upheld by a disciplinary panel.
The relegation-battling side had claimed wrongful dismissal following referee Lee Mason's decision to send Derry off after 15 minutes for a foul on Ashley Young and award a penalty to United, even though the winger had clearly been offside when he collected Wayne Rooney's through ball.
After the 2-0 defeat at Old Trafford, which leaves QPR out of the relegation zone on goal difference alone, manager Mark Hughes said that he believed several managers were "losing faith" with officials.
"You do discuss it before every game," said Hughes. "You worry more about decisions going against you and it shouldn't be like that. You should have confidence that the referee will get the key decisions right.
"Just lately a lot of managers have lost faith in them. It is a difficult job. You have to be strong and really clear. You have to be 100 per cent right to give the decisions. At the moment people are guessing and hoping that they get it correct. That was the case today."
Rangers chief executive Phil Beard was unimpressed with Young's reaction to the minimal contact from Derry, tweeting: "Difficult to take after watching numerous replays but Ashley Young could partner Tom Daley at the Olympics."