Paramedics treated five people at the scene and rushed three patients to hospital. Two others were discharged at the scene.
Enquiries into the circumstances continue, the Met said.
A B12 bus operated by Go-Ahead London Transport appeared to have mounted the pavement and toppled a small brick wall before travelling into the grassy front garden of a property.
The front bonnet of the car involved in the collision has been severely damaged.
There have been no arrests.
ERITH: Five people were injured, with three of them being taken to hospital, after a bus and car collided in Bexley Road at the junction with Park Crescent Road shortly after 7am this morning. Pix: Nathan Long. pic.twitter.com/esiCtU1LZe
— Kent 999s (@Kent_999s) September 5, 2023
A London Ambulance Service spokesperson said: “We were called at 7.05am to reports of a road traffic collision involving a bus and a car at the junction between Park Crescent Road and Bexley Road, Erith.
“We sent two ambulance crews and an incident response officer to the scene.
“We treated five patients. We took three patients to hospital and discharged the other two at the scene.”
Louise Cheeseman, Transport for London (TfL)’s Director of Buses, said: “We are aware of an incident of a car colliding with a bus in Erith on Tuesday 5th September.
“We understand this may have been distressing for those involvedand we have support available for anyone affected by this incident.
“A full investigation is underway and we are working with Go Ahead, the operator, to establish what happened.”
Anyone affected by serious incidents on the TfL network can contact the Sarah Hope Line on 0343 222 5678.