Adams has named an unchanged team for the last three games and is keen to do so again at Underhill.
But for defenders Purse and Chilvers and striker Hughes, all of whom are in their 30's, it would be a third match in the space of a week.
"It definitely helps when you can pick the same team over and over again because everyone is aware of their roles and responsibilities," said Adams.
"But we have to be mindful of the fact we have three players in the team who are over 30. Maybe three games in a week might be a bit too much for them, but we'll assess them up to the game and pick a side accordingly.
"If I feel they've had enough recovery time, and they're right, then I'll pick them again."
Should Adams need to make any changes he has defender Adam Yates, midfielders Chris Shuker, Sam Morsy and Chris Birchall and strikers Calvin Andrew and Ben Williamson ready to come into the starting XI.
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