Addison has missed the last two games with an ankle injury, and is not expected to make a first-team return for a further three to four weeks.
Howe will also make last-minute decisions on midfield duo Marc Pugh and Harry Arter, as both face late fitness tests.
Stephane Zubar is unlikely to feature against Joe Dunne's side as he continues his recovery from a hamstring problem.
The Frenchman is nearing a return after over two months on the sidelines, but will not be risked on Saturday.
The Cherries are enjoying a 12-match unbeaten run, and they will be looking to record their 10th win from their last 13 games against the U's, to continue their march towards the play-off places.
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- Harry Arter
- Marc Pugh