Pedro scored the winner for world champions Spain in a 1-0 victory over France in Paris on Tuesday which put them back on top of their group in qualifying for next year's World Cup finals.
The 25-year-old was already suspended for next Tuesday's Champions League quarter-final first leg against Paris St Germain, but now misses Saturday's league trip to Celta Vigo and is a doubt for the visit of Real Mallorca the following weekend.
Pedro is the second Barca player to pick up an injury on international duty this month, with Spain left-back Jordi Alba suffering a hamstring strain.
The duo join Adriano Correia and Carles Puyol in the treatment room.
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- Champions League