The 20-year-old missed the 2-0 win after he picked up two bookings in the Johnstone's Paint Trophy draw against Oxford.
His return could see veteran centre-back Darren Purse drop to the bench.
Argyle boss Carl Fletcher has no fresh injury or suspension concerns ahead of the game and could be tempted to stick with the same XI that recorded his side's first win in 10 games against the Minstermen.
Fletcher's men sit 20th in npower League Two, 13 places beneath Saturday's opponents who they have not beaten away from home since September 2001.
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