Collins has made only four appearances for the Iron this season due to a long-term Achilles injury and although he featured against Gillingham at the beginning of last month he has played no part since.
The Iron will be without skipper Paul Reid again as he sits out the last of a three-game ban following his recent dismissal against Notts County, and fellow centre-half David Mirfin is still out with a knee injury.
Striker Adda Djeziri, a recent loan signing from Blackpool, is hoping to feature in the squad and goalkeeper Steve Mildenhall has recovered from a knee injury he sustained against Bury.
Scunthorpe are chasing their first league win in four matches.
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