The 19-year-old scored a superb equaliser, his third goal in two Europa League matches, as the Latics maintained their unbeaten record with a 1-1 draw at home to Rubin Kazan.
Powell was the stand-out performer and Coyle hopes to be able to tease more out of the teenager during his season-long loan.
"After the season with us he will be good enough to go back and challenge (for a place at United)," said Coyle.
"He still has a lot to improve on and he will tell you that but he has ability. He is such a talented lad and I just want to get the best out of him.
"I'm giving him a platform and a wee bit of wisdom from my own playing days but he has to push himself on and you could see from his performance he is doing that.
"All I can do is try and impart any knowledge and experience I have as a player and a striker.
"As a manager I've worked with many international strikers and there is no doubt Nick Powell can go on to achieve that level.
"His aspirations should be after this season to go and challenge for Manchester United's first team and that will put him in the eyes of the national team.
"I believe he has everything in his locker, with progression and natural development, to attain that level.
"There's no doubt. I have been fortunate to work with young players and when they get a platform, they blossom, they flourish and he is doing that.
"Aside from his goal he has pace to burn and is so elegant running the with ball."
The result kept Wigan in second place in the group, two behind Rubin and two ahead of Maribor, but after an improved second-half performance Coyle felt they had missed an opportunity, especially with late efforts from Callum McManaman and Marc-Antoine Fortune denied.
"We knew coming into the game we were going to play against quality opposition," he added.
"They have tremendous European pedigree in the last five or six years, have been to Barcelona and won and narrowly lost to Chelsea in the quarter-finals last year.
"My players stood toe-to-toe and - with all due respect to Rubin, who are a very good side - we should have won the game. It was an outstanding performance from Wigan."
Rubin coach Kurban Berdyev felt his side were disappointing.
"In certain situations we were not playing as good as we could," he said.
"It was a dangerous standard but in general the result was as expected."