The duo were expected to feature in the midweek FA Cup second round replay with Rotherham but the game was postponed.
Both have missed the last three games through suspension and striker Hughes is expected to battle it out with Chris Iwelumo for a starting place.
Campbell-Ryce should replace fellow midfielder Alan Judge who serves a one-match suspension after picking up his fifth yellow card of the season at Yeovil last weekend.
Defender Manny Smith made a return to action for the reserves following four months on the sidelines with a knee problem, but is unlikely to feature.
Andre Boucaud, Jordan Stewart, and Tom Williams continue to be ruled out through injury.
- Sports & Recreation
- Chris Iwelumo