Midfielder Southern (Achilles) returned to action for the first time in nearly two months in the weekend win at Wolves and is hoping to make his first start since New Year's Day.
Striker Beckford, on loan from Leicester, has started the last three games on the substitutes' bench, but struck a match-winning second-half double at Wolves after replacing Neil Danns in the second half and is pushing for a recall.
Winger Danny Ward (groin) and right-back Jack Hunt (hamstring) are expected to miss out again, but striker Lee Novak will return to contention after missing out at the weekend due to personal reasons.
Manager Mark Robins has no new injury or suspension problems as his side bid to extend the two-point gap between themselves and the bottom three.
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