The former Manchester City youngster sustained a broken nose when he clashed heads with Adam Chicksen during the Tykes' 3-1 win over MK Dons in the fifth round of the FA Cup on Saturday.
Etuhu, who received treatment on the pitch for seven minutes before being substituted off, looks set to miss out on Tuesday, with Jim O'Brien his most likely replacement.
Otherwise, manager David Flitcroft is unlikely to make any further changes to his starting XI.
Striker Jason Scotland, who has stepped off the substitutes' bench in his side's last four matches, is in contention to make his first start for the club.
- Sports & Recreation