Ferguson collected two bookings before half-time in the Seasiders' last home game against Crystal Palace, where his team-mates held out for Matt Phillips to fire a late winner.
The former Scotland international is likely to be a straight replacement for Isaiah Osbourne, who begins a three-match ban after having his appeal to overturn last weekend's red card in the 1-1 draw with Nottingham Forest rejected.
Gary MacKenzie is set to resume duties at centre-back having suffered a blow to the head at the City Ground that left him complaining of double vision.
The on-loan MK Dons defender is back in training alongside Gary Taylor-Fletcher (hamstring) but this game is expected to come too soon for the long-serving forward.
- Sports & Recreation
- Isaiah Osbourne
- Matt Phillips