The central-defender is rated as "touch and go" by Reds boss Billy Davies to recover from a back injury in time for Saturday's lunchtime kick-off at the City Ground. Wilson has missed the last two matches with the problem he sustained during the 2-2 home draw with Middlesbrough.
Davies made 11 changes in midweek for the Capital One Cup tie at Burnley and the Scot is expected to do something similar against the Rams.
Nathaniel Chalobah, signed on loan from Chelsea last week, should make his home debut.
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