The 25-year-old, back in the international fold after ending his self-imposed exile in the wake of Giovanni Trapattoni's departure last month, was hurt after landing awkwardly as he made a 35th-minute challenge at the Aviva Stadium.
He was treated on the pitch for several minutes with club manager Roberto Martinez watching from the stands, and was eventually carried off on a stretcher.
An FAI statement issued via its Twitter account said: "Darron Gibson has been assessed by our team doc and will return to his club tomorrow for a scan with suspected knee ligament damage."
Gibson, his club and Ireland will hope the damage is not serious with the player having only just recovered from injury.
- Sports & Recreation
- Darron Gibson
- Giovanni Trapattoni