Hogan's goals underlined the home side's superiority and moved Keith Hill's men five points clear of the Sky Bet League Two play-off places.
The U's missed the first clear chance in the 21st minute. John Mullins met Danny Rose's back-post cross and saw his initial effort blocked by Josh Lillis' legs and when the ball rebounded back to him, he screwed a shot wide of the unguarded goal from four yards.
Four minutes into the second half Hogan netted his second when he collected the ball 40 yards from goal and drifted past three defenders to go one-on-one with Oxford goalkeeper Ryan Clarke. Hogan saw his first effort blocked but seized on the rebound to double his tally.
Hogan's hat-trick came in the 62nd minute when he scuffed Michael Rose's free-kick into the corner of the net to take his tally to the season to 19 goals.
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