Boss Steve Davis revealed his intentions after the 1-0 win against Sheffield United which ended the club's four-match losing streak that had followed their Johnstone's Paint Trophy final win.
With Alex unable to finish higher than their current position - barring a 22-goal swing between Notts County and themselves - Davis will take the opportunity to showcase the latest batch of young prospects.
However, only goalkeeper Ben Garrett is expected to make his debut, with a number of graduates already first-team regulars.
Defenders Harry Davis and Kelvin Mellor and striker Ajay Leitch-Smith are expected to retain their places in the team, while skipper Luke Murphy hopes to shake off a groin problem to lead the side
The likes of George Ray, Matt Tootle, Ollie Turton and Max Clayton could be called on to play.
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- Sheffield United