Leading goalscorer Aluko is nursing a slight tear in his Achilles and could be sidelined for up to eight weeks, while wing-back Elmohamady has been recalled from his season-long loan early by parent club Sunderland.
Nick Proschwitz and Jay Simpson were partnered together up front in the midweek FA Cup replay win at Leyton Orient and could keep their spots, while Liam Rosenior is likely to continue in place of Egypt international Elmohamady, who returned to the Stadium of Light earlier in the week.
Midfielder Tom Cairney is hoping to force his way back into the starting line-up after firing the winning goal at Orient in extra time, while defenders Abdoulaye Faye and Jack Hobbs are expected to be recalled to the starting line-up.
The Tigers, still in second place, are looking to bounce back from last week's home defeat to Sheffield Wednesday - their first loss in 10 matches.
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