James will serve a one-match ban against the Latics after being sent off for two yellow card offences during the Foxes' defeat at Charlton prior to the international break. The only other absentee is expected to be Sean St Ledger as he continues to make progress in his recovery from a knee injury.
Andy King (Wales), Kasper Schmeichel (Denmark) and Chris Wood (New Zealand) have returned from international duty unscathed but captain Wes Morgan only got back from winning his first cap for Jamaica on Thursday so manager Nigel Pearson will have to decide if it is too late for him to be involved on Saturday.
Midfielder Dean Hammond will hope to make his Leicester debut after joining the club from Southampton at the end of August.
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- Kasper Schmeichel