Joe Garner's double helped North End to a 2-1 win at Prenton Park.
Garner's header opened the scoring after 18 minutes before Ash Taylor equalised for the hosts just before the break.
But Garner, leading scorer for the Lilywhites this season, took his tally to 16 goals in all competitions with a 52nd-minute effort.
Moore said: "If you look at the possession both sides have had and the goals that they've scored, it was self-destruct from our point of view.
"It was one long cross into the box - the defenders are waiting for the keeper to come - just head it clear and then moan about it. The second goal the lad had all day to stick it in where he wanted.
"But we huffed and puffed and I can't fault the effort and commitment.
"We started off 4-4-2, that wasn't working so we had to change it after 20 minutes. We brought (Jason) Koumas on, then we managed to get on the ball and play, because if we hadn't have done that then they would have had the ball all day.
"Sometimes you have to make those big decisions early on and if we hadn't we would have been in big trouble.
"But they've got better players, they're a good side. They're one of the best sides we've played."
- Sports & Recreation
- Joe Garner