The Irishman, who has started every league game this campaign, suffered a groin strain in an accident at home and will miss his side's final match of the season.
Chris Dunn is expected to make his first league appearance of the season in Murphy's absence.
Defender Jordan Stewart picked up a groin injury in last Saturday's defeat to Leyton Orient and is expected to miss out, but Blair Adams could come back into the side to replace him.
Adams has been sidelined since early February with a knee injury but he is expected to return to full fitness in time to play some part against the Magpies.
- Sports & Recreation
- Chris Dunn
- Jordan Stewart